Insulin-like Growth Factor 1 (IGF-1)

CPT: 84305

Synonyms

Insulin-like Growth Factors Somatomedin C

Expected Turnaround Time

3 - 5 days

Specimen Requirements


Specimen

Serum

Volume

0.5 mL

Minimum Volume

0.1 mL (Note: This volume does not allow for repeat testing.)

Container

Red-top tube or gel-barrier tube

Collection

Separate within one hour; transfer into a plastic transport tube.

Storage Instructions

Ship frozen on dry ice.

Test Details


Methodology

Blocking radioimmunoassay (RIA) after acid:alcohol extraction

Reference Interval

Term Preterm Age Range (ng/mL) Mean (ng/mL) Range (ng/mL) Mean (ng/mL) Birth 15 - 109 59 21 - 93 51 2m 15 - 109 55 23 - 163 81 4m 7 - 124 50 23 - 171 74 6m 7 - 93 41 15 - 132 61 12m 15 - 101 56 15 - 179 77 Male Female Age Range (ng/mL) Mean (ng/mL) Range (ng/mL) Mean (ng/mL) 1-2y 30 - 122 76 56 - 144 100 Age Tanner Stage Female Range Female Mean 3y 1 26 - 162 77 4y 1 32 - 179 88 5y 1 39 - 198 100 6y 1 47 - 217 113 7y 1 55 - 238 127 8y 1 64 - 259 142 8y 2 89 - 369 181 9y 1 74 - 282 158 9y 2 96 - 399 196 9y 3 192 - 568 350 10y 1 85 - 306 175 10y 2 104 - 431 212 10y 3 192 - 568 350 10y 4 and 5 279 - 664 446 11y 1 97 - 332 194 11y 2 112 - 466 229 11y 3 192 - 568 350 11y 4 and 5 268 - 646 433 12y 1 110 - 358 213 12y 2 121 - 504 247 12y 3 192 - 568 350 12y 4 and 5 248 - 612 406 13y 2 131 - 545 267 13y 3 192 - 568 350 13y 4 and 5 229 - 579 380 14y 2 136 - 566 278 14y 3 192 - 568 350 14y 4 and 5 211 - 547 356 15y 3 192 - 568 350 15y 4 and 5 194 - 516 332 16y 4 and 5 177 - 487 309 17y 4 and 5 162 - 458 287 18y 4 and 5 147 - 430 266 Age Tanner Stage Male Range Male Mean 3y 1 20 - 141 63 4y 1 25 - 157 73 5y 1 30 - 174 84 6y 1 37 - 192 96 7y 1 44 - 211 109 8y 1 52 - 231 123 8y 2 and 3 39 - 264 121 9y 1 61 - 252 137 9y 2 and 3 52 - 304 146 10y 1 71 - 275 153 10y 2 and 3 67 - 347 174 11y 1 82 - 299 170 11y 2 and 3 86 - 393 206 11y 4 and 5 277 - 673 449 12y 1 93 - 324 188 12y 2 and 3 106 - 443 240 12y 4 and 5 265 - 652 433 13y 1 106 - 350 207 13y 2 and 3 130 - 497 277 13y 4 and 5 241 - 612 401 14y 1 120 - 377 227 14y 2 and 3 156 - 554 318 14y 4 and 5 220 - 574 372 15y 1 127 - 391 237 15y 2 and 3 185 - 616 362 15y 4 and 5 199 - 537 343 16y 2 and 3 201 - 648 386 16y 4 and 5 180 - 501 316 17y 4 and 5 161 - 467 290 18y 4 and 5 144 - 434 266 Male Female Age Range (ng/mL) Mean (ng/mL) Range (ng/mL) Mean (ng/mL) 19 - 20y 281 - 510 371 217 - 475 323 21 - 30y 155 - 432 289 87 - 368 237 31 - 40y 132 - 333 226 106 - 368 225 41 - 50y 121 - 237 160 118 - 298 205 51 - 60y 68 - 245 153 53 - 287 172 61 - 70y 60 - 220 132 75 - 263 180 71 - 80y 36 - 215 131 54 - 205 156