ZnT8 Antibodies

CPT: 86341

Expected Turnaround Time

3-10 days

Specimen Requirements


Specimen

Serum (preferred) or plasma (heparin)

Volume

0.5 mL

Minimum Volume

0.2 mL (Note: This volume does not allow for repeat testing.)

Container

Red-top tube, gel-barrier tube, or green-top (heparin) tube

Collection

Serum or plasma must be separated from cells within 45 minutes of venipuncture. Transfer separated serum or plasma to a plastic transport tube. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

Storage Instructions

Freeze. Stable at room temperature, refrigerated, or frozen for seven days. Freeze/thaw cycles: stable x6.

Causes for Rejection

Gross hemolysis, lipemic specimen, EDTA plasma

Test Details


Use

Detects zinc transporter 8 autoantibodies (ZnT8), an autoimmune diabetes marker that is instrumental in the diagnosis of new-onset type 1 diabetes

Methodology

Enzyme-linked immunosorbent assay (ELISA)